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UCI Anti-Cancer Challenge

October 10, 2026

Through your involvement in the UC Irvine Anti-Cancer Challenge, you have made more cancer research progress possible.

IMPACT SINCE 2017

7.7 million raised by UC Irvine Anti-Cancer Challenge participants and donors; 155 pilot projects and early phase clinical trials funded, $60 million in extramural funding awarded to UC Irvine researchers for grants that stemmed from pilot projects
31 specific community needs addressed as a result of Anti-Cancer Challenge seed funding
11 clinical trials accruing patients as a result of Anti-Cancer Challenge seed funding
7 companies launched as a result of Anti-Cancer Challenge seed funding

View the complete list of Anti-Cancer Challenge funded projects and awardees.

Download the full research portfolio.
  
 
HEAR FROM THE RESEARCHERS

Play YouTube video titled Answers for Cancer: Featuring Dr. Senthil and Dr. Dayyani

View YouTube Playlist of Researcher Interview Shorts: David Fruman, PhD, Claudia Benevente, PhD, Selma Masri, PhD and Alexandre Chan, PharmD, PhD, MPH  Interview Play YouTube video: Dr. Richard Van Etten Interview


  WHERE THE FUNDS GO
The UCI Health Chao Family Comprehensive Cancer Center illuminated at night, representing where Anti-Cancer Challenge funds are directed
Every penny of the funds raised by UC Irvine Anti-Cancer Challenge participants are directed towards advancing innovative basic, translational and clinical cancer research that will lead to the next breakthroughs in cancer treatment at the UCI Health Chao Family Comprehensive Cancer Center.

UCI Health Chao Family Comprehensive Cancer Center is a national leader in cancer research, education and treatment. Established in 1989 as Orange County’s first cancer center and designated as NCI “comprehensive” since 1994, the cancer center meets rigorous criteria aimed at providing world-class patient care and innovative research to Orange County, the second most densely populated county in California.
 

TRANSFORMATIVE IMPACT: SUCCESS STORIES
  
Dr. Senthil and Dr. Dayyani
A novel approach to advanced stomach cancer

Determined to improve treatment options for patients with late-stage gastric cancer, UCI Health oncologists Maheswari Senthil, MD, and Farshid Dayyani, MD, PhD, have joined forces to develop a novel clinical trial. Together, they have launched STOPGAP, an innovative phase 2 clinical trial that takes a three-pronged approach to treating gastric carcinomatosis. It is supported in part by seed money from the UC Irvine Anti-Cancer Challenge.


Read the full article here.

 
 Dr. Ganesan Image
Finding the genetic switch to stop tumor growth
“We’ve made a new chemical that’s never been made before. We show how the drug works. And we show that the drug slows cancer growth,” says UCI Health’s Dr. Anand Ganesan. “That would not be possible without grants from the National Institutes of Health (NIH) and the UC Irvine Anti-Cancer Challenge,” he says, which helped pave the way for his decade-plus research effort to identify genes that are activated in cancer and to develop ways to prevent those genes from sending signals that spur the disease.

Read the full article here.